Clinical Trials for Hemochromatosis

• Stroke With Transfusions Changing to Hydroxyurea (SWiTCH)
  
  Compare transfusions and chelation therapy with hydroxyurea and phlebotomy therapy for the prevention of secondary stroke and management of iron overload in children with sickle cell anemia
• Treatment of Hemochromatosis
  
  Evaluate the effectiveness of a test called MCV in guiding phlebotomy therapy in patients with hemochromatosis
• Cardiac Function in Patients With Hereditary Hemochromatosis
  
  This study will examine the effect of iron buildup in the hearts of patients with hereditary hemochromatosis (HH), a genetic disease that causes the body to accumulate excess amounts of iron.
• Hemochromatosis:Phlebotomy Versus Erythrocytapheresis Therapy
  
  In this project we plan to evaluate the effectiveness of erythrocytapheresis against phlebotomy, both regarding the impact on the reduction in hemochromatosis as well as reduction in patient 'burden'.
• Study Using Deferiprone Alone or in Combination With Desferrioxamine in Iron Overloaded Transfusion-Dependent Patients
  
  Systematical (retro- and prospective) investigation of long-term safety (toxicity assessment according to CTCAE v3.0) and efficacy of deferiprone given alone or in combination with desferrioxamine
• Screening of Hepatocellular Carcinoma in Patients With Compensated Cirrhosis
  
  Liver carcinoma is the main complication of cirrhosis. Treatment of symptomatic or large tumors is disappointing. Regular ultrasonographic screening of small curable tumors is currently recommended,
• Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization
  
  Problems of neonatal compatibility between a mother and child of mothers with Hemochromatosis